A string of PKK attacks have targeted Turkish security forces since a two-year ceasefire collapsed in July 2015.
Cizre has been the subject of several curfews in the past few months by Turkish authorities fighting the PKK.
A large car bomb has exploded outside a police building in Cizre, south-east Turkey, killing eight policemen and injuring more than 45, reports say.
The explosion occurred at 07:00 (04:00 GMT). Pictures showed a multi-storey building in ruins.
It is unclear who carried out the attack, but Turkish media blamed the banned Kurdistan Workers Party, PKK.
Await for further details.
